An Introduction to Molecular Biotechnology- Fundamentals, by Michael Wink
By Michael Wink
Molecular biotechnology keeps to triumph, as this textbook testifies - edited by means of one of many educational pioneers within the box and written via skilled pros. This thoroughly revised moment version covers the complete spectrum, from the basics of molecular and phone biology, through an outline of normal tools and applied sciences, the appliance of a number of the "-omics", and the improvement of novel drug pursuits, correct as much as the importance of procedure biology in biotechnology. the total is rounded off by means of an creation to commercial biotechnology in addition to chapters on corporation origin, patent legislations and advertising.
the hot version features:
- huge layout and whole colour throughout
- confirmed constitution based on fundamentals, equipment, major issues and fiscal perspectives
- New sections on approach biology, RNA interference, microscopic strategies, excessive throughput sequencing, laser purposes, biocatalysis, present biomedical functions and drug approval
- Optimized educating with studying goals, a word list containing round 800 entries, over 500 very important abbreviations and extra reading.
the single source in the event you are heavily drawn to the topic.
Bonus fabric to be had on-line at no cost: www.wiley-vch.de/home/molecbiotech
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Additional info for An Introduction to Molecular Biotechnology- Fundamentals, Methods and Applications
Bond types: hydrogen bonds, ionic bonds, van der Waals forces, and disulfide bridges. 5 kJ mol–1). · Hydrophobic attractions. 8 summarizes the most common hydrogen bonds present in a cell. Electronegative atoms, such as oxygen and nitrogen, try to withdraw electrons from neighboring atoms such as hydrogen. This results in oxygen and nitrogen having a slight negative charge, while hydrogen is slightly positively charged. Positive and negative charges attract one another. The resulting attractions are known either as hydrogen bonds or hydrogen bridges.
Most of the cellular building blocks are inert molecules that are not prone to react chemically. Significant activation energy has to be overcome in order to start an energy-consuming chemical reaction. In the laboratory this can be achieved by heating and adding acids or bases. In biological systems evolution has developed enzymes as biological catalysts that are able to catalyze all necessary reactions without higher temperatures being necessary. Enzymes do not change the reaction equilibrium, but usually alter the reaction rate.
Biomembranes generate a diffusion barrier and enclose all cells, and in eukaryotes enclose all internal organelles (mitochondria, plastids) and compartments (see Chapter 3). 3 describes the structure of phospholipids. 3) and the third is linked by an ester bond to a phosphate residue. An additional ester bond links the negatively charged phosphate residue to either an amino alcohol (choline or ethanolamine), the amino acid serine, or the sugar alcohol inositol. 3 Important fatty acids in membrane lipids.