Advances in Clinical Cytology by Leopold G. Koss and Dulcie V. Coleman (Auth.)

Molecular Biology

By Leopold G. Koss and Dulcie V. Coleman (Auth.)

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FERENCZY, A. (1976) Studies on the cytodynamics of human endometrial regeneration. II. Transmission electron microscopy and histochemistry, American Journal of Obstetrics and Gynecology, 124, 582-595 31. GORDON, M. (1975) Cyclic changes in the fine structure of the epithelial cells of human endometrium, International Review of Cytology, 42, 127-172 • 32. WYNN, R. M. (1977) Histology and ultrastructure of the human endometrium. In Biology of the Uterus, pp. 341-374. Ed. by R. M. Wynn. New York: Plenum Press 42 Ultrastructural dynamics of endometrial hyperplasia and neoplasia 33.

G. J. (1967) Enzyme histochemistry of adenocarcinoma of the endometrium including hormone induced changes, American Journal of Obstetrics and Gynecology, 99, 173-181 23. , LINDELL, A. and PERSSON, B. H. (1971) Binding of estradiol-17ß to human cancer tissues of the female genital tract, Cancer Research, 31, 1895-1898 2 4 . , KARJ ALAINEN, O. a n d LUUKKAINEN, T. ( 1 9 7 1 ) I n - vitro binding of progesterone by the human endometrium during the menstrual cycle and by hyperplastic, atrophic and carcinomatous endometrium, American Journal of Obstetrics and Gynecology, 111, 205-210 25.

13). Free ribosomes and primary lysosomal activity are also diminished in early neoplasia. The neoplastic cells contain microfilaments, which are also seen in cyclic proliferative as well as in hyperplastic endometrium, but in the former they are deposited in a haphazard fashion and often have a perinuclear location. 14). 15)1214, they are essentially identical and provide supportive submicroscopic evi­ dence that the cells in carcinoma in situ are indeed neoplastic and are the immediate precursors of invasive carcinoma14,41.

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